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HLA and lung transplantation

Liya Ju, Caroline Suberbielle, Xiaofan Li, Nuala Mooney, Dominique Charron

Frontiers of Medicine 2019, Volume 13, Issue 3,   Pages 298-313 doi: 10.1007/s11684-018-0636-x

Abstract: While the association between antibody mediated rejection and allograft damage has been well establishedThe role of the antibody mediated immune response is discussed as well as the importance of pre-transplantFinally, potential mechanisms, which may act individually or in combination, of antibody mediated damage

Keywords： leukocyte antigen class I and II     lung transplantation     mismatch     obliterans bronchiolitis     alloantibody     antibodymediated rejection    

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RGO-MXene membranes with wettability-regulated channels: improved water permeability and electro-enhanced rejection

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 1, doi: 10.1007/s11783-023-1601-8

Abstract:

● Electroconductive RGO-MXene membranes were fabricated.

Keywords： Reduced graphene oxide     MXene     Membrane     Water permeance     Dye rejection     Electro-assistance    

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Simulation of the optimal heat rejection pressure for transcritical CO

Junlan YANG, Yitai MA, Minxia LI, Hua TIAN

Frontiers in Energy 2010, Volume 4, Issue 4,   Pages 522-526 doi: 10.1007/s11708-010-0027-8

Abstract: The simulation results show that a maximum COP exists at the optimal heat rejection pressure not onlyAlso, the optimal heat rejection pressures of the throttle valve cycle are greater than those of theIn order to further obtain correlation of the optimal heat rejection pressure for transcritical CO expanderBased on the simulation results, the values of the optimal heat rejection pressure for the expander cycle

Keywords： transcritical CO2 cycle     optimal heat rejection pressure     simulation     expander    

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Novel Ag-AgBr decorated composite membrane for dye rejection and photodegradation under visible light

Yixing Wang, Liheng Dai, Kai Qu, Lu Qin, Linzhou Zhuang, Hu Yang, Zhi Xu

Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 4,   Pages 892-901 doi: 10.1007/s11705-020-2011-0

Abstract: photocatalytic membranes showed a relatively high water permeation flux (~ 47 L·m ·h ·bar ) and dyes rejectionAdditionally, the composite membranes exhibited potential long-term stability for dye/salt separation (dye rejection: ~97%; salt rejection: ~6.5%).

Keywords： Ag-AgBr     dye rejection     photodegradation     visible light    

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Ultrasound-mediated targeted microbubbles: a new vehicle for cancer therapy

Junxiao YE, Huining HE, Junbo GONG, Weibing DONG, Yongzhuo HUANG, Jianxin WANG, Guanyi CHEN, Victor C YANG

Frontiers of Chemical Science and Engineering 2013, Volume 7, Issue 1,   Pages 20-28 doi: 10.1007/s11705-013-1311-z

Abstract: ultrasound microbubble contrast agent can carry gene drugs and so on to the target tissue, as well as mediated

Keywords： ultrasound-mediated     targeted microbubbles     cancer    

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Gut microbiota and its implications in small bowel transplantation

Chenyang Wang, Qiurong Li, Jieshou Li

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 239-248 doi: 10.1007/s11684-018-0617-0

Abstract: In fact, several studies indicated that acute and chronic allograft rejection in small bowel transplantationSBT and the potential roles of these alterations in the development of acute and chronic allograft rejectionmicrobiota as a microbial marker and/or therapeutic target for the predication and intervention of allograft rejectionexpected to provide valuable insights into the role of gut microbiota in the development of allograft rejection

Keywords： gut microbiota     small bowel transplantation     acute rejection     chronic rejection     mucosal immunity     biomarker    

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BGB-A445, a novel non-ligand-blocking agonistic anti-OX40 antibody, exhibits superior immune activation

Frontiers of Medicine doi: 10.1007/s11684-023-0996-8

Abstract: Here, we discovered that BGB-A445, a non-ligand-competitive agonistic anti-OX40 antibody currently underdose-dependently and significantly depleted regulatory T cells in vitro and in vivo via antibody-dependentdemonstrated robust and dose-dependent antitumor efficacy, whereas the ligand-competitive anti-OX40 antibodyFurthermore, BGB-A445 demonstrated a strong combination antitumor effect with an anti-PD-1 antibody.

Keywords： BGB-A445     OX40     agonistic antibody     OX40L noncompetitive    

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Passive antibody therapy in emerging infectious diseases

Frontiers of Medicine doi: 10.1007/s11684-023-1021-y

Abstract: Antibody therapies encompassing convalescent plasma, hyperimmunoglobulin, and neutralizing monoclonalIn addition, the prospects of applying antibody therapy against VOCs was assessed, offering insights

Keywords： SARS-CoV-2     COVID-19     convalescent plasma     hyperimmunoglobulin     neutralizing monoclonal antibodies    

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Role of membrane and compound properties in affecting the rejection of pharmaceuticals by different RO

Yang-ying Zhao, Fan-xin Kong, Zhi Wang, Hong-wei Yang, Xiao-mao Wang, Yuefeng F. Xie, T. David Waite

Frontiers of Environmental Science & Engineering 2017, Volume 11, Issue 6, doi: 10.1007/s11783-017-0975-x

Abstract: Efforts were also devoted to understand the effect of adsorption on the rejection performance of eachResults showed that NF90 performed similarly to ESPA1 with mean rejection higher than 95%.NF270 outperformed HL in terms of both water permeability and PhAC rejection higher than 90%.Electrostatic effects were more significant in PhAC rejection by loose NF membranes than tight NF andThe adverse effect of adsorption on rejection by HL and ESPA1 was more substantial than NF270 and NF90

Keywords： Trace organic compounds (TrOCs)     Nanofiltration (NF)     Adsorption     Membrane properties     Water treatment    

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Regulation of exogenous bFGF gene mediated by recombinant adeno-associated virus

Ke SONG, Nianjing RAO, Meiling CHEN, Yingguang CAO

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 158-163 doi: 10.1007/s11684-009-0042-5

Abstract: The regulatory effect of basic fibroblast growth factor (bFGF) mediated by recombinant adeno-associated

Keywords： tetracycline regulatory system     adeno-associated virus     basic fibroblast growth factor     gene regulation    

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Sulfur mediated heavy metal biogeochemical cycles in coastal wetlands: From sediments, rhizosphere to

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 8, doi: 10.1007/s11783-022-1523-x

Abstract:

• In sediments, the transformation of sulfides may lead to the release of heavy metals.

Keywords： Coastal wetland     Heavy metal     Sulfur     Biogeochemical cycle    

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Microbial mediated arsenic biotransformation in wetlands

Si-Yu Zhang, Paul N. Williams, Jinming Luo, Yong-Guan Zhu

Frontiers of Environmental Science & Engineering 2017, Volume 11, Issue 1, doi: 10.1007/s11783-017-0893-y

Abstract: Among these fine-scale events, microbial mediated As biotransformations contribute most to the elementdocument some of these key advances, with focuses on the implications that wetlands and their microbial mediatedtransformation pathways have on the global As cycle, the chemistries of microbial mediated As oxidation

Keywords： Arsenic     Wetland     Microbes     Switch    

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Production of a polyclonal antibody to the VP26 nucleocapsid protein of white spot syndrome virus (wssv

Suchera LOYPRASERT-THANANIMIT, Akrapon SALEEDANG, Proespichaya KANATHARANA, Panote THAVARUNGKUL, Wilaiwan CHOTIGEAT

Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 2,   Pages 216-223 doi: 10.1007/s11705-012-1289-y

Abstract: The objective of this work was to produce a polyclonal antibody against VP26 and use it as a biosensorprotein (rVP26) was produced in (BL21), purified and used for immunizing rabbits to obtain a polyclonal antibody

Keywords： recombinant protein     polyclonal antibody     label-free biosensor     impedance     white spot syndrome virus (WSSV    

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on porphyrinic triazine-based frameworks with excellent biocompatibility for conversion of CO in H-mediated

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 12,   Pages 1761-1771 doi: 10.1007/s11705-022-2195-6

Abstract: Microbial electrosynthesis is a promising alternative to directly convert CO2 into long-chain compounds by coupling inorganic electrocatalysis with biosynthetic systems. However, problems arose that the conventional electrocatalysts for hydrogen evolution may produce extensive by-products of reactive oxygen species and cause severe metal leaching, both of which induce strong toxicity toward microorganisms. Moreover, poor stability of electrocatalysts cannot be qualified for long-term operation. These problems may result in poor biocompatibility between electrocatalysts and microorganisms. To solve the bottleneck problem, Co anchored on porphyrinic triazine-based frameworks was synthesized as the electrocatalyst for hydrogen evolution and further coupled with Cupriavidus necator H16. It showed high selectivity for a four-electron pathway of oxygen reduction reaction and low production of reactive oxygen species, owing to the synergistic effect of Co–Nx modulating the charge distribution and adsorption energy of intermediates. Additionally, low metal leaching and excellent stability were observed, which may be attributed to low content of Co and the stabilizing effect of metalloporphyrins. Hence, the electrocatalyst exhibited excellent biocompatibility. Finally, the microbial electrosynthesis system equipped with the electrocatalyst successfully converted CO2 to poly-β-hydroxybutyrate. This work drew up a novel strategy for enhancing the biocompatibility of electrocatalysts in microbial electrosynthesis system.

Keywords： microbial electrosynthesis     hydrogen evolution reaction     metalloporphyrins     biocompatibility     CO2 conversion    

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Growth suppression of colorectal cancer expressing S492R EGFR by monoclonal antibody CH12

Qiongna Dong, Bizhi Shi, Min Zhou, Huiping Gao, Xiaoying Luo, Zonghai Li, Hua Jiang

Frontiers of Medicine 2019, Volume 13, Issue 1,   Pages 83-93 doi: 10.1007/s11684-019-0682-z

Abstract: Recently, treatments using cetuximab, also named C225, an anti-EGFR monoclonal antibody, for CRC haveand S492R EGFR accelerate the growth of CRC cells in vitro and in vivo and monoclonal antibodyFurthermore, mAb CH12 showed significantly stronger growth suppression activities and induced a more potent antibody-dependent

Keywords： S492R EGFR ectodomain mutation     colorectal cancer     mAb CH12     immunnotherapy    

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Title Author Date Type Operation

HLA and lung transplantation

Liya Ju, Caroline Suberbielle, Xiaofan Li, Nuala Mooney, Dominique Charron

Journal Article

RGO-MXene membranes with wettability-regulated channels: improved water permeability and electro-enhanced rejection

Journal Article

Simulation of the optimal heat rejection pressure for transcritical CO

Junlan YANG, Yitai MA, Minxia LI, Hua TIAN

Journal Article

Novel Ag-AgBr decorated composite membrane for dye rejection and photodegradation under visible light

Yixing Wang, Liheng Dai, Kai Qu, Lu Qin, Linzhou Zhuang, Hu Yang, Zhi Xu

Journal Article

Ultrasound-mediated targeted microbubbles: a new vehicle for cancer therapy

Junxiao YE, Huining HE, Junbo GONG, Weibing DONG, Yongzhuo HUANG, Jianxin WANG, Guanyi CHEN, Victor C YANG

Journal Article

Gut microbiota and its implications in small bowel transplantation

Chenyang Wang, Qiurong Li, Jieshou Li

Journal Article

BGB-A445, a novel non-ligand-blocking agonistic anti-OX40 antibody, exhibits superior immune activation

Journal Article

Passive antibody therapy in emerging infectious diseases

Journal Article

Role of membrane and compound properties in affecting the rejection of pharmaceuticals by different RO

Yang-ying Zhao, Fan-xin Kong, Zhi Wang, Hong-wei Yang, Xiao-mao Wang, Yuefeng F. Xie, T. David Waite

Journal Article

Regulation of exogenous bFGF gene mediated by recombinant adeno-associated virus

Ke SONG, Nianjing RAO, Meiling CHEN, Yingguang CAO

Journal Article

Sulfur mediated heavy metal biogeochemical cycles in coastal wetlands: From sediments, rhizosphere to

Journal Article

Microbial mediated arsenic biotransformation in wetlands

Si-Yu Zhang, Paul N. Williams, Jinming Luo, Yong-Guan Zhu

Journal Article

Production of a polyclonal antibody to the VP26 nucleocapsid protein of white spot syndrome virus (wssv

Suchera LOYPRASERT-THANANIMIT, Akrapon SALEEDANG, Proespichaya KANATHARANA, Panote THAVARUNGKUL, Wilaiwan CHOTIGEAT

Journal Article

on porphyrinic triazine-based frameworks with excellent biocompatibility for conversion of CO in H-mediated

Journal Article

Growth suppression of colorectal cancer expressing S492R EGFR by monoclonal antibody CH12

Qiongna Dong, Bizhi Shi, Min Zhou, Huiping Gao, Xiaoying Luo, Zonghai Li, Hua Jiang

Journal Article